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The Effect of Endurance Exercise on High-Sensitivity C - ReactiveProtein in Serum of Inactive Allergic Asthma Participants

Received: 19 Aug 2022
Revised: 26 Sep 2022
Accepted: 18 Oct 2022

Daniel Tarmast (PhD)

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The aim of this study was to evaluate the effects of endurance training on serum CRP (C-reactive protein) levels in adult asthma patients. For this purpose, pre and post aerobic training (3 times-weekly/ 3 months) blood samples were taken after overnight fast in 32 adult men with asthma patients that wasrandomly divided to exercise and control groups. Anthropometrical indexes were also monitored in two occasions. All data changes were compared by t - tests. At baseline, there were no differences in the serum CRP, body weight and other anthropometrical indexes between the two groups. Compared to pre-training, the CRP levels decreased significantly after aerobic training in the exercise group but not in the control subjects. We observed a significant decrease in all anthropometrical indexes in exercise group. All paper remained without any changes in the control group. Thus, we conclude that the endurance exercise activity improves systemic inflammation in asthma patients.


Keywords: Asthma Patients, Endurance Exercise, High-Sensitivity C-Reactive Protein.


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1)Amina H, Abdul G, Abdul K, Jasim M .2010. Association Between C Reactive Protein and Asthma. TurkishToraxDergisi 11(3), 098 -104.

2)Butland BK, Strachan DP, Rudnicka AR. 2008.C-reactive protein, obesity, atopy and asthma symptoms in middle- aged British adults. EurRespir J 32, 77-84.

4)Danesh J, Wheeler JG, Hirschfield GM. 2004.C–reactive protein and other circulating markers of inflammationin the prediction of coronary heart disease. N Eng J Med 350, 387-97.

de Salles BF, Simão R, Fleck SJ, Dias I, Kraemer-Aguiar LG, Bouskela E. 2010. Effects of resistance training on cytokines.Int J Sports Med 31(7), 441-50.

5)Doron A, Inon R, Mordechay Y, Arthur K, Ophir A, Ron S, Peter B. 2006. Inverse Association between Pulmonary Function and C -reactive protein in Apparently Healthy Subjects. Am J RespirCrit Care Med 174, 626–632.

7)Ebrahim R , Hassan E, Hossein A, Vajihe C,Armin R. 2011. Armin Razi Evaluation of HighSensitivity C-Reactive Protein in Acute Asthma Tanaffos 11(1), 32-37.

8)Eizadi M, Kohandel M, kasbparast JR M, Sarshin A. 2011. Hs-CRP and TNF- alpha inresponse to a stepwise incremental bicycle test in adult obese men 1(3), 35-43.

9)Ford ES. 2003. Asthma, body mass index, and Creactive protein among US adults. Journal of Asthma 40(7), 733- 10) Ford ES. 2005. The epidemiology of obesity and asthma. J Allergy ClinImmunol 115, 897-909.

11)Gann WQ, Man SFP, Senthilselvan A. 2004.Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and meta analysis. Thorax 59, 574-80.

12)Heidenfelder B, Johnson M, Hudgens E, Inmon J, Hamilton RG, Neas L, Gallagher JE. 2010.Increased plasma reactive oxidant levels and their relationship to blood cells, total IgE, and allergenspecificIgE levels in asthmatic children. J Asthma 47(1), 106-11.

13)Hotamisligil GS. 2006. Inflammation and metabolic disorders. Nature 444, 860-7.Huang H, Iida KT, Sone H, Ajisaka R. 2007.The regulation of adiponectin receptors expression by acute exercise in mice.ExpClinEndocrinol Diabetes 115(7),417-22.

15)Jousilahti P, Salomaa V, Hakala K, Rasi V, Vantera E, Palosuo T. 2002. The association of sensitive inflammation markers with bronchial asthma.Annals of Allergy, Asthma and Immunology89(4), 381-5.

16)Jousilahti P, Salomaa V, Hakala K, RasiV,Vantera E, Palosuo T. 2002. The association of sensitive inflammation markers with bronchial asthma.Ann Allergy Asthma Immunol 89, 381-5.

17)Jousilahti P, Salomaa V, Hakala K. 2002. The association of sensitive systemic inflammation markers with bronchial asthma.Ann Allergy Asthma Immunol 89, 381-5.

18)Jedariforoughi A. A qualitative survey about a patient s experiences and expectations of meeting healthcare professionals during multiple acute hospitalizations and follow up periods. Doctmedico Journal. 2022;2(1):180-93.

19)Jedariforoughi A, Karimpour F. The review of recent Developments in use of artificial intelligence in cancer detection. www doctmedico com. 2021.

20)Jedariforoughi A. Review article about developments in cancer prevention in public health in recent years. www doctmedico com. 2021.

21)Khosravaniardakani S. Vaping Products And Asthma In Youths: A Review Of The Prospective Study. International Journal of Medical Investigation. 2022;11(1):0-. (link)

22)Khosravaniardakani S, Bokov DO, Mahmudiono T, Hashemi SS, Nikrad N, Rabieemotmaen S, et al. Obesity Accelerates Leukocyte Telomere Length Shortening in Apparently Healthy Adults: A Meta-Analysis. Frontiers in nutrition. 2022:139. (link)

23)Khosravaniardakani S. The Effect of Cigarette and Its Nicotine Content on The Heart Health. International Journal of New Chemistry. 2022;9:26-41. (link)

24)Kony S, Zureik M, Driss F, Neukirch C, Leynaert B, Neukirch F. 2004. Association of bronchial hyperresponsiveness and lung function with C-reactive protein (CRP): a population based study. Thorax 59, 892-6. 25)Kony S, Zureik M, Driss F. 2004. Association of BHR and lung function with CRP: a population based study. Thorax 59, 1-5.

26)Mendall MA, Strachan DP, Butland BK. 2000.C-reactive protein: relation to total mortality, cardiovascular mortality and cardiovascular risk factors in men. Eur Heart J 21, 1584-90.

27)Mendall MA, Strachan DP, Butland BK. 2000.C-reactive protein: relation to total mortality, cardiovascular mortality and cardiovascular risk factors in men. Eur Heart J 21, 1584-90.

28)O’Connor GT, Sparrow D, Weiss ST. 1995. Aprospective longitudinal study of methacholine airway responsiveness as a predictor of pulmonary-function decline: the Normative Aging Study. Am J RespirCrit Care Med 152, 87-92.

29)Olafsdottir IS, Gislason T, Thjodleifsson B, Olafsson I, Gislason D, Jögi R. 2005. C reactive protein levels are increased in nonallergic but not allergic asthma: a multicentre epidemiological study. Thorax 60(6), 451- 4.

30)Ridker PM. 2000. C-reactive protein and othermarkers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 342,836–843.

31)Rijcken BJ, Schouten JP, Xu X. 1995. Airway hyperresponsiveness to histamine associated with accelerated decline in FEV1. Am J RespirCrit Care Med 51, 1377-82.

32)Sahoo RC, Acharya PR, Noushad TH, Anand R, Acharya VK, Sahu KR. 2009. A Study of HighSensitivityC - reactive protein in Bronchial Asthma. Indian journal of chest diseases & allied sciences 51(4), 213-6.

33)Tang Z, Yuan L, Gu C, Liu Y, Zhu L. 2005. Effect of exercise on the expression of adiponectin mRNA and GLUT4 mRNA in type 2 diabetic rats.J HuazhongUnivSciTechnolog Med Sci 25(2), 191-3.

34)Tice JA. 2003. The relation of C-reactive protein levels to total and cardiovascular mortality in older U.S. women. Am J Med 114, 199–205.

35)Tilg H, Moschen AR. 2006. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 6, 772-83.

30)Varady KA, Tussing L, Bhutani S, Braunschweig CL. 2009. Degree of weight loss required to improve adipokine concentrations and decrease fat cell size in severely obese women.Metabolism 2009 58(8), 1096-101.

31)Yudkin JS, Stehouwer CD, Emeis JJ. 1999. C reactive protein in healthy subjects: associations with obesity, insulin resistance and endothelial dysfunction: a potential role for cytokines originating from adiposetissue? ArteriosclerThrombVasc Biol. 19, 972-8.


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